Zithromax (Azithromycin) is an antibiotic very popular in primary care. E ‘widely used for a number of indications, as a community acquired respiratory tract infections and tonsillitis. I find it particularly useful because it is easy once daily dosing and short course of five days. Compliance patient has improved. Zithromax when it was first introduced and are educated me drugs, I noticed that there was a possibility of zithromax increase the effect of raising Coumadin and a patient of INR. For a couple of years, every patient I had to Coumadin had their INR’s been a couple of extra times during therapy with zithromax.

Once I did not find any significant changes in their INR. Because of cost and time, I stopped doing the extra work laboratory. I recently treated a male patient in his mid sixties with zithromax for the community has acquired bronchitis. He is to anticoagulant Coumadin for a mechanical aortic valve. For months, his INR was constant, without changes in the dosage of his Coumadin.

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